Mitochondrial Function Profile

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Test Details for Ordering
Test Mitochondrial Function Profile
Laboratory Acumen and Biolab
Price £230.00
Sample required blood
To order this test, please, go to Ordering Tests.

Please, make sure you have read When not to use this website to ascertain whether having this test is an appropriate and safe course of action for you.


  • Please, kindly note that the practice is experiencing a high volume of orders for the Mitochondrial function profile and inevitably there is some delay in processing the orders. Each order will be acknowledged and processed as soon as possible.
  • If you are ordering the test from outside the UK, please read the page Mitochondrial function profile for overseas CFS sufferers - how to get it done


This blood test combines several tests which together assess mitochondrial function and identify where the problem areas with energy production are. It is exceptionally useful for chronic fatigue sufferers as it gives clear indications for a treatment regime. More details of the test can be found in CFS - The Central Cause: Mitochondrial Failure

Mitochondrial function profile is made up of the following individual tests:

  • ATP profiles;
  • NAD (functional B3);
  • SODase;
  • L-carnitine;
  • Cell-free DNA

All the above tests are performed at Acumen Laboratory

  • Co-enzyme Q10 - this test is performed at Biolab Medical Unit

About "ATP profiles"

The most significant test in the Mitochondrial function profile is called "ATP profiles". It was developed by Dr John McLaren-Howard. The result is made up of three elements. First of all, it measures the rate at which ATP is recycled in cells. Because production of ATP is highly dependent on magnesium status so the first part of the test studies this aspect.

The second part of the test measures the efficiency with which ATP is made from ADP. If this is abnormal, then this could be as a result of magnesium deficiency, and/or low levels of Co-enzyme Q10, and/or low levels of vitamin B3 (NAD) and/or low levels of acetyl L-carnitine.

The third possibility is that the protein which transports ATP and ADP across mitochondrial membranes is impaired and this is also measured.


blood - three blood tubes are required


The kit for this test includes a a green topped,a purple topped and a gold topped blood tube, two plastic blood tube carriers and plastic bags for sealing the samples, two request forms (one for Acumen Laboratory and the other for Biolab Medical Unit) and two pre-paid envelopes for sending the samples to the laboratories.

The samples in the green-top tube and purple-top tube go to Acumen Laboratory and the sample in the gold-top tube goes to Biolab.


You will need to have blood taken for this test - you need to either contact your own GP surgery or find a competent professional (nurse, doctor, etc), who will take blood for you.

If you are sending samples from abroad - please read Mitochondrial function profile for overseas CFS sufferers - how to get it done


How much will it cost

The price of the profile is £230.00 and I charge £80 for my letter to your GP. The price for my letter reflects the fact that the letter effectively interprets 6 tests and I give detailed advice about a range of issues arising from the questionnaire.

Turnaround time

Once the test samples are received at the lab, it takes about a week for most of the results to come back, but the Co Q10 takes longer - up to 10 days. The results come to me and I dictate the letter. This is then typed, signed and ready for posting or e-mailing. You can ask for it to be emailed to your doctor and yourself. Due to a very high volume of orders, currently this process may take up to 5 weeks.

Message to overseas CFS sufferers interested in the Mitochondrial function profile (MFP)

This test is available world-wide. Please, note that the batch of tests making up the MFP are blood tests and you will need to make arrangements to have blood taken by a qualified phlebotomist. You will also need to make your arrangements for shipping the samples to the UK BEFORE HAVING BLOOD TAKEN!

Mitochondrial function profile for overseas CFS sufferers - how to get it done provides information about ordering the test and shipping the samples to UK. It is very important that you follow all the instructions in that page about the labelling of your package to avoid delays at Customs!

The availability of nutritional supplements to non-UK residents

All the supplements necessary for recovery I normally supply. However, because of difficulties involved in shipping them overseas, I recommend they be accessed from the following suppliers:

  • The sole US distributor for Vegepa and E-EPA90 Omega based supplements is:
Peter Stankowski from Pharmepa Corporation, E-mail:

There are other websites of nutritional supplements manufacturers and distributors - some carry the same products at competitive prices. As for the mineral mix and mineral drops, you will need to find the products that will give you amounts of individual minerals which are as close as possible to my recommendations.


Sarah Myhill Limited  :: Registered in England and Wales  :: Registration No. 4545198
Registered Office: Upper Weston, Llangunllo, Knighton, Powys, Wales LD7 1SL, UK. Tel 01547 550331 | Fax 01547 550339

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