Reprogram the immune system with micro-immunotherapy
[UPDATED NOVEMBER 2024]
[MEDICAL STUDIES SECTION - section 13 - ADDED AUGUST 2023]
Micro-Immunotherapy Website
You will find lots of useful information here:
Micro Immunotherapy International Medical Experience
(By Dr Franziska Meuschel and Dr Sarah Myhill)
Introduction
Most chronic disease processes are associated with chronic inflammation and this causes unpleasant symptoms. Something must be done! The principles of treatment are:
- identify the cause and remove it (turn off the gas to the cooker) – see our book “The Infection Game -life is an arms”
- extinguish the inflammatory fire (smother the flames) – see “Ecological Medicine – the antidote to Big Pharma”.
- but if that is not enough, reprogramme the immune system (learn not to make the same mistake again! Not easy- old habits die hard) Again see “Ecological Medicine – the antidote to Big Pharma”.
Micro-immunotherapy
Micro-immunotherapy was developed by Dr Maurice Jenaer in the 1970s and is in wide use in Germany, France, Italy, Austria and other countries. It helps us to reprogramme the immune system. It is comprised of tiny doses, but not homeopathic doses, of bio-identical mediators (messengers) of inflammation namely: neurotransmitters, cytokines, growth factors, hormones and specific nucleic acids. Some combinations of specific nucleic acids interfere with viral RNA reproduction and this explains anti-viral effects.
It can be used in any condition associated with acute or chronic inflammation which may be due to chronic infection with virus (not bacteria or fungi), allergy or autoimmunity. It can be combined with other treatments and is particularly helpful for the very sick patient who is intolerant to all else. It is an effective, safe and simple intervention and that appeals greatly to me!
It can also be safely combined with any other treatments including diet, nutritional supplements, glandular extracts, anti-microbial drugs and herbs and even prescription medication.
This treatment is very safe and there have been no cases of major allergic reactions to it.
It does contain tiny doses of lactose and sucrose which only rarely cause problems.
It is completely safe for children to use.
Micro-immunotherapy is fast becoming my preferred treatment of any condition associated with immune over-activity or under-activity because is is so effective, safe and easy to administer. Details of HOW to use these remedies are given below.
I am training Practitioners from NHW to use micro-immunotherapy and so go to the NHW website to find someone to prescribe. Alternatively come to one of my workshops.
For details of how these work please see these pages:
The final link is my Sales Website page for currently available workshops - do keep checking back as new workshops are offered all the time
Indications
Micro-immunotherapy for ACUTE viral infection
Apply Groundhog ACUTE
| Clinical problem | Preparation Labo’Life | Clinical picture | Dose | Notes – all below work well in parallel with antivirals |
|---|---|---|---|---|
| Any acute infection, children and adults | EID | Sudden illness, malaise. Possibly fever, rash, aching.
Good for immune deficiency states so has wide application to treat and prevent many infections. This makes it a popular remedy. Particularly good for respiratory and urinary infections/ |
At the first sign of infection take up to 4 capsules daily for 2 days. THEN reduce according to symptoms. | See “The Infection Game” for details of treating all acute infections |
| Genital Herpes | HERP | Acute and chronic recurrent herpes 1 and 2 (ie genital and oral herpes) outbreaks | At the first sign take up to 4 capsules spaced through the day for 2 days. THEN reduce 3, then 2 then to one daily depending on how quickly the infection is clearing.
For recurrent infections use daily for one year then 10 capsules per month. |
Again can be combined with antivirals
ALSO use topical Lugol’s iodine 15%. And Groundhog ACUTE |
| For herpes prevention | Take one daily for at least 6 months | |||
| Varicella zoster | ZONA | Chicken pox and shingles | At the first sign take up to 4 capsules daily until rash starts to go THEN reduce to one daily | Again can be combined with antivirals
ALSO use topical Lugol’s iodine 15%. And Groundhog ACUTE |
| Following shingles always look for the under-lying cause of immuno- suppression - -which may be a tumour |
Micro-immunotherapy for CHRONIC viral infection
Apply Groundhog CHRONIC
We need some evidence of infection from the clinical history and picture, supported by antibody titres and possibly Armin Labs tests. Broadly speaking if the IgG antibody titre is 5 times the higher limit of normal then this suggests the immune system is active against that virus and the specific remedy can be applied. If not sure start with 2L EID. This is especially useful to help those who seem to pick up every cough and cold going.
If lymphocytes are high then this points to an active immune system fighting a viral infection.
EBV is the major driver in post viral ME. Suspect when there is positive viral serology vis:
- IgM viral capsid high and/or
- IgG viral capsid antigen antibodies 5 times baseline and/or
- IgG nuclear antigen antibodies 5 times baseline.
- IgG nuclear antigen antibodies zero or near baseline in a patient with a severe case of EBV / mono in the history.
| Clinical problem | Preparation Labo’Life | Clinical picture | Dose | Notes |
|---|---|---|---|---|
| Chronic EBV [Epstein Barr Virus] | EBV | 80% of post viral ME is EBV driven.EBV is involved in so many other diseases including auto-immunity and cancer that this is a very widely used remedy. This is one of the most used remedies | Take one daily
Follow the sequence of 10 tabs |
May take 5-6 weeks to respond - -continue treatment for 6-12 months.This is the commonest and most useful preparation I use since EBV is a driver of many cases of ME, auto-immunity and cancer |
| Chronic CMV [Cytomegalovirus] | CMV | Many PWME carry this virus too | Take one daily. Follow the sequence of 10 tabs | |
| Almost any virus! Or not sure which | EID | Good for patients who seem to pick up every virus going OR those who cannot tolerate specific remedies | Ditto | Other remedies could be added in after 2 months - typically the EBV remedy |
| Works well for children picking up viruses at school - often useful in the Autumn term! | Children receive the same dose as adults | |||
| Post herpetic neuralgia, ME that was zoster triggered | ZONA | One daily | ||
| ME triggered by HHV 6 (roseola),HHV 7 (pityriasis rosea),Respiratory Syncitial virus,Parvovirus | EID | One daily | ||
| ME triggered by Hepatitis B and C | HC | One daily | ||
| ME associated with streptococcus, staphylococcus, borrelia, yersinia, candida | EID | One daily | ||
| ME associated with Chlamydia | CHLA | One daily | ||
| ME associated with toxoplasma | TOXO | One daily | ||
| Papilloma virus HPV | PAPI | Associated with cervical cancer | One daily | It is still essential to attend for regular cervical smear screening tests |
| HIV infection | S1 | One daily | Must be taken in parallel with all other HIV therapies |
Micro-immunotherapy for non-specific use when an incitant is not clear
Apply Groundhog CHRONIC
There are many remedies that can be used on clinical grounds and which do not require diagnostic blood tests. Those in most common use are:
| Clinical problem | Preparation Labo’Life | Clinical picture | Dose | Notes |
|---|---|---|---|---|
| Arthritis | ARTH | Painful joints eg osteoarthritis, rheumatoid arthritis or gout. This is another popular remedy useful in any condition associated with inflammation. Often used to help people to wean off NSAIs. Some clinicians use this to treat arteriosclerosis, endometriosis and even obesity! | With acute pain take up to 4 daily, then tail off according to clinical response to 1 one daily | Arthritis is so often driven by microbes from the fermenting gut - -so PK diet and vit C to bowel tolerance essential! See Vitamin C - learn to use this vital tool well – the key is getting the dose right and The Paleo Ketogenic Diet - this is a diet which we all should follow |
| Chronic inflammation | INFLAM | Widespread inflammation such as fibromyalgia, bursitis, tendinitis, synovitis | With acute pain take up to 4 daily, then tail off according to clinical response to 1 one daily | Ditto above |
| The above two remedies are often used together | ||||
| Disturbed sleep | SLEEP REG | Inflammation and sleep disturbance | Take one daily one hour before bedtime
Follow the sequence of 10 tabs |
We know that inflammation disturbs sleep |
| Brain going slow | MEM SENIOR | Foggy brain of ME or dementia | Ditto. Could use with remedy Mda | Has also been used in students swatting for exams with good results! |
| Depression | DEP | One daily | ||
| Inflammatory bowel disease | MICI | Crohn’s, ulcerative colitis | One daily | |
| Very sick patients | MISEN | Who seem to react to whatever is tried | One daily | The idea is to make the immune system less twitchy! |
| Macular degeneration | DMLA | One daily | Vitamin C to bowel tolerance is essential | |
| Parkinson’s disease | PARK | One daily | The sooner this can be started the better as it seems to slow progression of PD | |
| Psoriasis | PSO | One daily | This is a fungal driven disease | |
| Osteoporosis | OSTEO-N | One daily | ||
| other HPV warts eg verrucas | VERU | One daily | ||
| Anti-ageing | SEN | One daily | Can be combined with other remedies detailed above for poor memory, poor sleep, poor vision |
Micro-immunotherapy for Allergy
Apply Groundhog CHRONIC
| Clinical problem | Preparation Labo’Life | Clinical picture | Dose ALWAYS follow the numerical order as detailed on the blister packet (even if you forget to take a dose!) | Notes |
|---|---|---|---|---|
| Allergy to inhalants | ALERG | For acute inflammation such as hayfever | Use up to 4 capsules daily in 4 doses – following the numerical order detailed on the packet | Taken like this it has an anti-histamine like action |
| ... and possibly foods | ALERG | To prevent hayfever and possibly food allergies | Take one daily for 3 months before the season | Works reasonably well but probably not as effective as Enzyme Potentiated Desensitisation (EPD) |
Worsening with micro-immunotherapy is unusual
- Should this happen stop entirely for one week and then restart one 10 capsule cycle (one 10 capsule cycle constitutes a complete treatment sequence). If this is not tolerated either, (and this is common with the EBV remedy) then take only one sequence per month (10 capsules day 1 – 10 then 3 weeks break.)
- And/or try introducing EID in parallel. This may work as EID upregulates the response that the body is failing to mount on its own.
- OR revert to a remedy for very sick people such as MISEN or EID.
- OR it may be that you are using a remedy for inflammation that stimulates the immune system when it should be inhibited, or vice versa.
In such an event it is helpful to know if the immune system is over or under-reacting because then one can chose remedies that switch off the immune system or remedies that switch it on.
| Immune system is over-active | Immune system is under-active |
|---|---|
| Allergy, Auto-immunity | Susceptibility to infection – tendency to pick up any infection doing the rounds! |
| Oncological disease | |
| High inflammatory markers e.g. high ESR (>10), high C reactive protein, high plasma viscosity | Very low inflammatory markers e.g. ESR 1 or 2 |
| High white cell count (since the WCC is negatively skewed, my view is that at total WCC over 7 is suggestive of too much inflammation) | Sub-normal levels of white cells, lymphocytes or neutrophils |
Remember that in many acute and chronic infections the immune system is over-active and this is totally desirable. In this event try to identify the infection and use the appropriate remedy as above.
Lymphocyte typing can help as it tells us if there is over-reaction or under-reaction. However this test is only available in Germany, and bloods have to be there within 24 hours. You need a Practitioner to order this test.
Lymphocyte typing measures numbers of leucocytes, lymphocytes and subsets and natural killer cells. You need an expert to interpret these tests!
| Remedies that tend to stimulate the immune system | Anti-microbial or antiviral remedies |
| Remedies that tend to suppress the immune system | Remedies for allergy and inflammation e.g. ARTH INFLAM ALERG
SLEEPREG MISEN MEM SENIOR |
Micro-immunotherapy for cancer
Of course any such treatment must be done in parallel with conventional oncology.
| Solid tumours less than one year | C1 | 1-2 capsules daily (12 hour intervals) for one year or until in remission |
| Solid tumours one to five years | C2 | 1 capsule daily for 4 years after remission |
| Lymphatic leukaemia | C1 for one year then C2 | Same as above |
| Chronic myeloid leukaemia | CLM | 1-2 capsule daily (12 hour intervals) for one year or until in remission
Then 1 capsule daily for 4 years after remission |
| Multiple myeloma Waldenstrom’s | KAH | Ditto above |
| Hodgkin’s and non-Hodgkins lymphoma | CL 1 and then
CL2 PLUS EBV (because many lymphomas are EBV driven) |
2 capsules per day (12 hour intervals) for one year
1 capsule per day for 4 years |
| Brain tumours | TNM | 2 capsules a day (12 hour intervals) long term |
Dosing
- ALWAYS take capsules in strict numerical order, 10 capsule cycles. Each 10 capsule cycle represents a course.
- For acute infections one can take at an accelerated rate of up to 4 daily. Again they must be taken in strict order. 10 capsules therefore last 2.5 days. Again they must be taken as below, under the tongue, 30mins away from food or water.
- Take on rising by pouring the contents of capsule under the tongue and letting it dissolve. Do not eat or drink for at least 30 minutes. Do not swallow the capsule contents – hold under the tongue until they dissolve away. It contains some lactose and sucrose as an excipient but the amounts are tiny and rarely cause problems.
- You can take more than one course of micro-immunotherapy but capsules must be separated by 30 mins as above
- Once micro-immunotherapy is working well, it is suggested that low dose maintenance be used long term at the rate of 10 capsules for the first 10 days of each month (leaving a break of 3 weeks between each cycle of treatment).
- For chronic disease you must commit to at least 3 months of therapy.
More Information
For more information,please follow these links:
Accessing micro-immunotherapy
Please note that for CHRONIC DISEASE you need to commit to a course of treatment which is usually at least 6 months and possibly longer. We can supply 3 months' treatment at a time.
Accessing my advice directly
Please see My Services as to whether you can / wish to access my advice directly
Accessing my advice indirectly
This is a treatment that has to be recommended and prescribed by a health practitioner who understands how micro-immunotherapy is used. It is a very safe treatment that I believe should be easily available to all patients whose clinical picture suggests that they may benefit from it.
To this end I am happy to supply micro-immunotherapy on the recommendation of a micro-immunotherapy conversant NHW practitioner.
This treatment dovetails nicely with all my other interventions to treat CFS/ME including diet, nutritional supplements, detox regimes and prescription drugs.
Should any problems arise then either you or your practitioner can get in touch with me directly.
If you wish to try micro-immunotherapy and you are not one of my patients
- Find a practitioner who recommends the treatment. To access such please click on Natural Health Worldwide
Presently Lily [SEARCH UNDER QUALIFIED HEALTH PRACTITIONERS – fourth page] is prepared to help.
- That NHW practitioner will send a recommendation to me at Office (office@doctormyhill.co.uk) and I will ensure that the recommendation is appropriate and send my recommendation to Helen (helen@doctormyhill.co.uk)
- Please note that the recommending NHW practitioner may charge for their time in doing this.
- Helen will contact you directly to organise delivery.
When is micro-immunotherapy a potentially useful therapy?
Your NHW practitioner will look for the common clinical situations for which micro-immunotherapy might be a useful therapy. These situations are detailed below.
| Clinical Picture | Check list of other interventions. See my two books on CFS/ME and chronic infection.
Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis -it's mitochondria not hypochondria! The Infection Game - life is an arms race |
Remedy | Cost of three months' supply [as at March 2023] GBP |
|---|---|---|---|
| ME following Epstein Barr infection (glandular fever or mono) | The patient has put in place Groundhog Chronic interventions. You can see these at | EBV. This is one of the most used remedies | 225.00 |
| ME following CMV infection (clinically this looks like EBV) | Ditto | CMV | 225.00 |
| Patients who pick up every cough and cold going | Ditto | EID | 225.00 |
| Fibromyalgia | Ditto | INFLAM | 213.01 |
| Mitochondrial dysfunction | Ditto | MIREG | 257.54 |
| Arthritis | Ditto | ARTH | 189.00 |
| Foggy Brain | Ditto | MEM SENIOR | 189.00 |
| Disturbed sleep | Ditto | SLEEP REG | 189.00 |
| Recurrent cold sores and herpes genitalis | Ditto. A popular remedy that works reliably well | HERP | 225.00 |
| Recurrent shingles | Ditto. Again works reliably well | ZONA | 225.00 |
System for accessing micro-immunotherapy via Natural Health Worldwide
If you suffer from any of the above then I will be happy to support a trial.
Once you have made contact with your NHW practitioner have them fill in the form below and then simply email it to me at Office (office@doctormyhill.co.uk)
Exemplar form
| Practitioner name | Practitioner email | Patient name | Sex and age | Patient email | Clinical picture | Yes the patient has been appraised of and put in place as much as possible to treat | Which remedy recommended | Dr Myhill to check and OK – any comments? |
|---|---|---|---|---|---|---|---|---|
A worked example of a recommendation:
| Practitioner name | Practitioner email | Patient name | Sex and age | Patient email | Clinical picture | Yes the patient has been appraised of and put in place as much as possible to treat | Which remedy recommended | Dr Myhill to check and OK – any comments? |
|---|---|---|---|---|---|---|---|---|
| Wilma Flintstone | wilma@flintstone.co.uk | Fredelle Bloggs | F 54 | fredelle@bloggs.co.uk | Post viral ME, probably EBV | Yes | 2L EBV |
Labo'Life Patient Leaflet
Related Articles
- My book “The Infection Game -life is an arms race”
- My book "Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis -it's mitochondria not hypochondria!"
- My book “Ecological Medicine – the antidote to Big Pharma”.
- Groundhog ACUTE
- Groundhog CHRONIC
- Enzyme Potentiated Desensitisation (EPD)
- Zoom Starter Workshops for Ecological Medicine
- Myhill Workshop Weekends
- Vitamin C - learn to use this vital tool well – the key is getting the dose right
- The Paleo Ketogenic Diet - this is a diet which we all should follow
External Links
Medical Studies supportive of Micro-Immunotherapy
These medical studies either directly support the use of the preparations as above or lend support to the idea of using low or ultra low dose cytokines to effect immunological reprogramming.
- 2023 Jacques, C., Floris, I. National Library of Medicine 'How an Immune-Factor-Based Formulation of Micro-Immunotherapy Could Interfere with the Physiological Processes Involved in the Atopic March'
- 2023 Jacques, C., Floris, I. National Library of Medicine 'Special Focus on the Cellular Anti-Inflammatory Effects of Several Micro-Immunotherapy Formulations: Considerations Regarding Intestinal-, Immune-Axis-Related- and Neuronal-Inflammation Contexts'
- 2022 Jacques, C., Chatelais, M., Fekir, K., Brulefert, A., Floris, I. International Journal of Molecular Sciences 'The Unitary Micro-Immunotherapy Medicine Interferon-y (4 CH) Displays Similar Immunostimulatory and Immunomodulatory Effects than Those of Biologically Active Human Interferon-? on Various Cell Types'
- 2022 Jacques, C., Marchesi, I., Fiorentino, F. P., Chatelais, M., Libera, N., Appel, K., Lejeune, B., Floris, I. International Journal of Molecular Sciences 'A Micro-Immunotherapy Sequential Medicine MIM-seq Displays Immunomodulatory Effects on Human Macrophages and Anti-Tumor Properties towards In Vitro 2D and 3D Models of Colon Carcinoma and in an In Vivo Subcutaneous Xenograft Colon Carcinoma Model'
- 2021 Jacques, C., Chatelais, M., Fekir, K., Fauconnier, L., Mellier, M., Togbe, D., Floris, I. International Journal of Molecular Sciences 'The Micro-Immunotherapy Medicine 2LEID Exhibits an Immunostimulant Effect by Boosting Both Innate and Adaptive Immune Responses'
- 2021 Jacques, C., Lejeune, B., Floris, I. International Journal of Molecular Sciences 'Ultra-Low Dose Cytokines in Rheumatoid Arthritis, Three Birds with One Stone as the Rationale of the 2LARTH® Micro-Immunotherapy Treatment'
- 2020 Ferrà, M., Munar, M. García, L. Lejeune, B. Ramis, J.M., Monjo, M. Journal of Periodontology 'BMP4 micro-immunotherapy increases collagen deposition and reduces PGE2 release in human gingival fibroblasts and increases tissue viability of engineered 3D gingiva under inflammatory conditions'
- 2020 Floris, I., García-González, V., Palomares, B., Appel, K., Lejeune, B. International Journal of Rheumatology 'The Micro-Immunotherapy Medicine 2LARTH® Reduces Inflammation and Symptoms of Rheumatoid Arthritis In Vivo'
- 2020 Floris, I., Chenuet P., Togbe D., Volteau C., Lejeune B. Dose Response Journal 'Potential Role of the Micro-Immunotherapy Medicine 2LALERG® in the Treatment of Pollen-Induced Allergic Inflammation'
- 2020 Floris, I., Rose, T., Collado, J.A., Appel, K, Roesch, C., Lejeune, B. Dose Response Journal 'Pro-Inflamatory Cytokines at Ultra-Low Dose Exert Anti-Inflammatory Effect In Vitro: A Possible Mode of Action Involving Sub-Micron Particles?'
- 2019 Lilli, N., Révy, D., Robelet, S., Lejeune, B. Degenerative Neurological and Neuromuscular Disease – Dove Press journal 'Effect of the micro-immunotherapy medicine 2LPARK® on rat primary dopaminergic neurons after 6-OHDA injury: oxidative stress and survival evaluation in an in vitro model of Parkinson’s disease'
- 2019 Lilli, N., Révy, D., Volteau, C., Robelet, S., Lejeune, B. Biomedical & Life Sciences Journal 'Effect of 2LMISEN® on Long-Term Hippocampal Neurons Culture as a Screening Senescent Cells Model: p16INK4A and Caspase 3 Quantification'
- 2018 Floris, I., Lechner, J., Lejeune, B. Journal of Biological Regulators & Homeostatic Agents 'Follow-up of patients with systemic immunological diseases undergoing fatty-degenerative osteolysis of the jawbone surgery and treated with RANTES 27CH'
- 2018 Floris, I., Appel, K., Thorsten, R., Lejeune, B. Journal of Inflammation Research '2LARTH®, a micro-immunotherapy medicine exerts anti-inflammatory effects in vitro and reduces TNF-alpha and IL-1beta secretion'
- 2018 Mancini, F., Milardi, D., Carfagna, P., Grande, G., Miranda, V., De Cicco, A., Ricciardi, D., Pontecorvi, A., Marana, R., De Cicco, F. International Immunopharmacology 'Low-dose SKA Progesterone and Interleukin-10 modulate the inflammatory pathway in endometriotic cell lines'
- 2017 Marin-Martin, L.S., Giovannangeli, F., Bizzi, E., Massafra, U., Ballanti, E., Cassol, M., Migliore, A. GDrug Des Devel Ther 'An open randomized active-controlled clinical trial with low dose SKA cytokines versus DMARDs evaluating low disease activity maintenance in patients with rheumatoid arthritis'
- 2017 Tessaro, I., Modina, S., Lodde, V., Sivelli., Franciosi, F., Terzachi, L., Luchini, P., Rumio, C., Luciano, A. Journal of Reproductive Infertility 'Ultra-Low Dose of Follicle Stimulating Hormone and Progesterone Attenuate the Severity of Polycystic Ovary Syndrome Features in a Hyperandrogenized Mouse Model'
- 2017 Uberti, F., Bardelli, C., Morsanuto, V., Ghirlanda, S., Cochis A., Molinari, C. Cells, Tissues, Organs 'Stimulation of the Nonneuronal Cholinergic System by Highly Diluted Acetylcholine in Keratinocytes'
- 2016 Camps, A., Almolda, B., Gonzalez, B., Castellano, B. Homeopathy 'Microimmunotherapeutic administration of cytokines improve the clinical symptoms in EAE an animal model of multiple sclerosis'
- 2016 Barygina, V., Becatti, M., Lotti, T., Moretti, S., Taddei N., Fiorillo, C. Journal of Dermatological Science 'Low dose cytokines reduce oxidative stress in primary lesional fibroblasts obtained from psoriatic patients'
- 2016 Fiorito, F., Cantiello, A., Granato, G.E., Navas, L., Diffidenti, C., De Martino, L., Maharajan, V., Olivieri, F., Pagnini, U., Lovane, G. Comp Immunol microbiol Infect Dis. 'Clinical improvement in feline herpesvirus 1 infected cats by oral low dose of interleukin-12 plus interferon-gamma'
- 2016 Thomas, G., Cluzel, H., Lafon, J., Bruhwyl, J., Lejeune, B. Advances in Infectious Diseases 'Efficacy of 2LPAPI®, a Micro-Immunotherapy Drug, in Patients with High-Risk Papillomavirus Genital Infection'
- 2015 Barygina, V., Becatti, M., Lotti, T., Moretti, S., Taddei N., Fiorillo, C. Journal of Dermatological Science 'Treatment with low-dese cytokines reduces oxidative-mediated injury in perilesional keratinocytes from vitiligo skin'
- 2015 Lotti, T., Hercogovo, J., Wollina, U., Chokoeva, A.A., Zarrab, Z., Gianfaldoni, S., Roccia, M.G., Fioranelli, M., Tchernev, G. J Biol Regul Homeost Agents 'Vitiligo: successful combination treatment based on oral low dose cytokes and different topical treatments'
- 2015 Radice, E., Bellone, G., Miranda, V. Translational Oncology 'Enhancement of the Immunostimulatory Functions of Ex Vivo–Generated Dendritic Cells from Early-Stage Colon Cancer Patients by Consecutive Exposure to Low Doses of Sequential-Kinetic-Activated IL-4 and IL-12. A Preliminary Study'
- 2013 Cardani, D., Dusio, G., Luchini , P., Sciarabba, M., Solimene, U., Rumio, C. Gastroenterology Research 'Oral Administration of Interleukin-10 and Anti-IL-1 Antibody Ameliorates Experimental Intestinal Inflammation'
- 2012 D’Amico, L., Ruffini, E., Ferracini, R., Roato, I. Journal of Cancer Therapy Low Dose of IL-12 Stimulates T Cell Response in Culters of PBMCs Derived from Non Small Cell Lung Cancer Patients
- 2012 Mazzoli, S., Cai, T., Meacci, F., Addonisio, P., Dorfman, P. International Journal of High Dilution Research 'High Risk Human Papillomavirus genital infections in asymptomatic population: effectiveness of Micro-Immunotherapy'
- 2011 Van der Brempt, X., Cumps, J., Capieaux, E. Revue Française d’Allergologie 'Clinical efficacy of 2LALERG®, a new sublingual immunomodulatory treatment, in seasonal allergic rhinitis: A double-blind placebo-controlled study'
- 2009 Gariboldi, S., Palazzo, M., Zanobbio, L., Dusio, G., Mauro, V., Solimene, U., Cardani, D., Mantovani, M., Rumio, C. Pulmonary Pharmacology & Therapeutics 'Low dose oral administration of cytokines for treatment of allergic asthma'
- 2000 Jenaer, M., Henry, MF., García, A., Marichal, B. British Homeopathic Journal 'Evaluation of 2LHERP® in preventing recurrences of genital herpes'
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